What this calculator does
AST-to-ALT ratio (De Ritis ratio) works out compares two liver enzymes, sometimes used to point toward a pattern of liver injury. Enter your own figures above and the answer updates as you type: nothing is fixed in the code, so the result reflects exactly the numbers you supply.
The formula this calculator evaluates is printed under the tool and explained below, so you can check the working by hand or reuse it in a spreadsheet.
The formula
FormulaDe Ritis ratio = AST (U/L) / ALT (U/L)
The inputs explained
| Field | What to enter |
|---|---|
| AST (U/L) | A number, measured in U/L. Starts at 25. |
| ALT (U/L) | A number, measured in U/L. Starts at 25. |
Worked examples
Every figure in the tables below is produced by this page’s own calculator at build time, so the numbers and the tool always agree. Select any row to load that scenario.
How the answer changes with ast
Every other input is held at the calculator’s starting values while ast varies. Select any row to load that scenario into the calculator.
How the answer changes with ast
| AST (U/L) | AST-to-ALT ratio | Reading |
|---|---|---|
| 12.5 | 0.50 | Below 1: more typical of viral hepatitis or fatty liver disease |
| 18.75 | 0.75 | Below 1: more typical of viral hepatitis or fatty liver disease |
| 25 | 1.00 | Between 1 and 2: nonspecific |
| 37.5 | 1.50 | Between 1 and 2: nonspecific |
| 50 | 2.00 | Above 2: can suggest alcohol-related liver disease |
| 75 | 3.00 | Above 2: can suggest alcohol-related liver disease |