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Chemistry

Serial dilution series calculator

Final concentration after a series of equal-factor dilutions, and the concentration at each step.

What this calculator does

Serial dilution series works out final concentration after a series of equal-factor dilutions, and the concentration at each step. Enter your own figures above and the answer updates as you type: nothing is fixed in the code, so the result reflects exactly the numbers you supply.

The formula this calculator evaluates is printed under the tool and explained below, so you can check the working by hand or reuse it in a spreadsheet.

The formula

FormulaCₙ = C₀ / DFⁿ

The inputs explained

FieldWhat to enter
Initial concentration (CFU/mL)A number, measured in CFU/mL. Starts at 100000000.
Dilution factor per stepA number. Starts at 10.
Number of dilution stepsA number. Starts at 5.

Worked examples

Every figure in the tables below is produced by this page’s own calculator at build time, so the numbers and the tool always agree. Select any row to load that scenario.

How the answer changes with initial concentration

Every other input is held at the calculator’s starting values while initial concentration varies. Select any row to load that scenario into the calculator.

How the answer changes with initial concentration
Initial concentration (CFU/mL)Final concentrationTotal dilution factorLog₁₀ total dilution
50,000,000500 CFU/mL100,000×5.000
75,000,000750 CFU/mL100,000×5.000
100,000,0001,000 CFU/mL100,000×5.000
150,000,0001,500 CFU/mL100,000×5.000
200,000,0002,000 CFU/mL100,000×5.000
300,000,0003,000 CFU/mL100,000×5.000