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Biology

Allele frequency from genotype counts calculator

Direct-count allele frequencies for a two-allele gene from observed genotype numbers in a sample.

What this calculator does

Allele frequency from genotype counts works out direct-count allele frequencies for a two-allele gene from observed genotype numbers in a sample. Enter your own figures above and the answer updates as you type: nothing is fixed in the code, so the result reflects exactly the numbers you supply.

The formula this calculator evaluates is printed under the tool and explained below, so you can check the working by hand or reuse it in a spreadsheet.

The formula

Formulap = (2·N_AA + N_Aa) / 2N; q = (2·N_aa + N_Aa) / 2N

The inputs explained

FieldWhat to enter
Homozygous dominant count (AA)A number. Starts at 50.
Heterozygous count (Aa)A number. Starts at 40.
Homozygous recessive count (aa)A number. Starts at 10.

Worked examples

Every figure in the tables below is produced by this page’s own calculator at build time, so the numbers and the tool always agree. Select any row to load that scenario.

How the answer changes with homozygous dominant count (aa)

Every other input is held at the calculator’s starting values while homozygous dominant count (aa) varies. Select any row to load that scenario into the calculator.

How the answer changes with homozygous dominant count (aa)
Homozygous dominant count (AA)Dominant allele frequency (p)Recessive allele frequency (q)Individuals sampled
250.60000.400075
37.50.65710.342988
500.70000.3000100
750.76000.2400125
1000.80000.2000150
1500.85000.1500200